06-01-2009

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ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri

 

ORIGINAL RESEARCH ARTICLES


Ischemic Stroke In Patients With Systemic Cancer: Case Report Involving Eight Cases And Review Of Literature

Dr. Mustafa GÖKÇEa,Dr. Gülen DEMİRPOLATb

aNöroloji AD,aRadyoloji AD,Kahramanmaraş Sütçü İmam
Üniversitesi Tıp Fakültesi,Kahramanmaraş



Objective: After cerebral metastasis, stroke is the second most important cause of cerebral symptoms in cancer patients. Studies documented that the causes of stroke could be different in systemic cancer patients as compared with patients without cancer. These studies also suggested that cerebrovascular events were frequently due to hypercoagulability. Hypercoagulability may lead to nonbacterial thrombotic endocarditis, cerebral intravascular coagulation and venous occlusion in these patients. It was also reported that direct blood vessel compression by tumor or lebolization of tumor and treatment related side effects might lead to infarction. Ischemic stroke in systemic cancer patients was investigated in this study. Material and Methods: Imaging, laboratory and clinical findings of 8 ischemic stroke patients with cancer were retrospectively evaluated from hospital records. Results: Five ischemic stroke patients with cancer had similar findings with noncancer patients. However, 3 of the 8 patients had different clinical features. Although one of the 3 patients was old and had hypertension, his subacute progressive stroke with small vessel diseases could not be accounted to these risk factors. The remaining two were young stroke patients and conventional risk factors were not detected. Their primary cancers were Non-Hodgkin lymphoma, Hodgkin lymphoma and choriocarcinoma of testis. Conclusion: Although some stroke events in systemic cancer patients are similar in noncancer population, some may have different clinical pictures and etiopathogenic mechanisms.

Keywords: Cerebrovascular accident; neoplasms

Turkiye Klinikleri J Med Sci 2008, 28:450-455

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