ISSN: 1300-0292
İndekslendiği Dizinler: SCIENCE CITATION INDEX EXPANDED
CINAHL, Index Copernicus,
Chemical Abstracts (CA),
Excerpta Medica / EMBASE
Dil: Türkçe, İngilizce
İçerik: Orijinal Araştırma, Derleme, Editöre Mektup, Olgu Sunumu, Tıp Eğitimi, Tıbbi Kitap İncelemeleri
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Renal Amyloidosis And Periorbital Ecchymoses: Scientific Letter
Dr. Aysun ŞİKAR AKTÜRKa,Dr. Erkan DERVİŞOĞLU,Dr. Rebiay KIRANa,Dr. Betül KALENDERb
aDermatoloji AD,bİç Hastalıkları AD,Nefroloji BD,Kocaeli Üniversitesi Tıp Fakültesi,Kocaeli
Amyloidosis is a group disease that is characterized by deposited proteins in the skin and other organs. It is classified as cutaneous amyloidosis, systemic amyloidosis and heredofamilial amyloidosis. Purpuric lesions and ecchymoses are the most common skin findings in systemic amyloidosis. However, glossitis, macroglossia, bullous lesions, alopecia and cutis verticis gyrata may be seen. In patient with primer systemic amyloidosis, acquired hemostatic abnormalities, hyperfibrinolysis, coagulation factor deficiencies, platelet dysfunction and increased fragility of blood vessels can be regarded as the most important pathogenetic factors. The mechanism of the localised bleeding is not completely understood. Here, we presented a patient with renal amyloidosis and periorbital ecchymoses in order to emphasize the necessity for remembering systemic amyloidosis in the differential diagnoses of periorbital ecchymoses.Keywords: Amyloidosis; ecchymosisdTurkiye Klinikleri J Med Sci 2008, 28:548-550
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